The department was created in December 1960. Doctor of Philosophy, Associate Professor V.M. Nizhegorodov (1926-1999) was appointed as the first Head of department. He headed the department until 1994. The first staff of the department included teachers A.P. Voronin and V.G. Mironov, senior laboratory assistant L.V. Shepilova, preparatary T.N. Peragarulka and N.S. Belevichute. The first classes were held February 13, 1961. The department was moved to the biological sciences building in 1964 and to the main building of the medical institute – in 1975.
In 1994-2004 a Head of the Department was Doctor of Medical Sciences, Professor M.S. Amelyanchyk. In 2004-2011 department was headed by Doctor of Medical Sciences, Associate Professor E.I. Makshanova. From August 2011 a Head of the Department is Doctor of Medical Sciences, Professor I.A. Naumov.